Ctrl-Alt-Gender is a Gauteng based trans support space run by trans people for trans people. It provides a weekly safe space for trans people to explore, ask and find community.
Gender Dynamix is a Cape Town based non governmental organisation that seeks to advance, promote and defend the rights of trans and gender nonconforming persons in South Africa, Africa and globally.
Gender Queer is a support group for anyone living in South Africa who is not specifically FTM or MTF but do feel they are gender non-conforming (genderfluid, genderqueer, agender, etc) and need a safe space to explore their identities in which they can feel unconditionally supported and accepted is welcome to join this group.
Iranti is a Gauteng based media advocacy organisation defending the human rights of transgender, intersex and lesbian persons in Africa.
The Triangle Project is a Cape Town based non-profit human rights organisation offering professional services to ensure the full realisation of constitutional and human rights for lesbian, gay, bisexual, transgender and intersex (LGBTI) persons, their partners and families.
For a comprehensive list you can also visit Germaine’s site for a comprehensive list of support groups.